Pdf neurocognitive outcomes of individuals with a sex. We encourage you to take advantage of these studies. Males with xyy had normalrange iqs, but all three sct groups xxx, xxy, and xyy had marked dif. Xyy syndrome is a rare chromosomal disorder that affects males. Different mechanisms in klinefelter syndrome contribute to reduced bone mass and osteoporosis, which have a precocious onset and are detected in up to 40% of patients, irrespectively of. Less evidence was available for brain structure and for attention, social, and psychiatric outcomes. Common trisomies and sex chromosome variations cynthia m. The person is generally otherwise normal, including normal fertility the condition is generally not inherited from a persons parents but rather occurs as a result of a random event.
Sindrome 47, xyy genetic and rare diseases information. Xyy syndrome is a genetic condition in which a person has an extra y chromosome. For some males with this syndrome, signs and symptoms are barely noticeable. Please use one of the following formats to cite this article in your essay, paper or report. Associate professor of pediatrics and genetics the university of north carolina at chapel hill.
Normalmente varones tienen solamente una copia del cromosoma y y tienen 46 cromosomas total. For others, signs and symptoms may include learning disabilities, speech delay, low muscle tone hypotonia, and being taller than expected. Although many males with this condition are taller than average, the chromosomal change sometimes causes no unusual physical features. Pdf living with klinefelter syndrome 47,xxy trisomy x 47,xxx and 47, xyy popular colection. Xyy syndrome nord national organization for rare disorders. Most males with 47, xyy syndrome have normal production of the male sex hormone testosterone and normal sexual. Patient had all classical phenotypical features of trisomy 21 except, absence of epicanthal folds.
Twentyeight indexpersons died in the 47, xyy subgroup, four in the mosaic subgroup and four in the subgroup of others. Pdf living with klinefelter syndrome 47,xxy trisomy x. Get paid, travel for free and participate in making a difference for klinefelter syndrome research. Research for klinefelter syndrome living with xxy ryan. It is caused by the presence of an extra y chromosome. However, individuals with this syndrome have one x and two y chromosomes. Bone density and risk of osteoporosis in klinefelter syndrome. These may include being taller than average, acne, and an increased risk of learning problems. Trisomy 21 with xyy, indian journal of pediatrics 10. Trisomy 21 with xyy trisomy 21 with xyy parmar, ramesh. Nevertheless, most adults with scts lived independently. Mortality was significantly increased in 47, xyy persons in total p xyy syndrome is characterized by an extra copy of the y chromosome in each of a males cells. Many have no symptoms, but some are more significantly affected.